Immunomodulatory and antitumour properties of Psoralea corylifolia seeds

Fitoterapia. 2000 Jun;71(3):223-31. doi: 10.1016/s0367-326x(99)00151-3.

Abstract

Psoralea corylifolia seed extract has been found to stimulate the immune system in mice. Administration of the extract was found to inhibit EAC ascitic tumour growth and stimulate natural killer cell activity, antibody-dependent cellular cytotoxicity, antibody-forming cells and the antibody complement-mediated cytotoxicity during tumour development.

MeSH terms

  • Adjuvants, Immunologic / pharmacology*
  • Animals
  • Antineoplastic Agents / pharmacology*
  • Antineoplastic Agents / therapeutic use
  • Carcinoma, Ehrlich Tumor / drug therapy*
  • Disease Models, Animal
  • Killer Cells, Natural / drug effects*
  • Male
  • Mice
  • Mice, Inbred BALB C
  • Plant Extracts / pharmacology*
  • Plant Extracts / therapeutic use
  • Plants, Medicinal*

Substances

  • Adjuvants, Immunologic
  • Antineoplastic Agents
  • Plant Extracts